Paraguay’s state utility ANDE and the International Atomic Energy Agency have formalized a non-binding technical cooperation agreement to assess small modular reactor technology as part of the country’s 2050 energy policy diversification strategy. The framework establishes capacity-building and knowledge exchange mechanisms without creating immediate legal or financial obligations, while Asunción hosts a regional week-long conference on SMR financing involving U.S. Department of Energy participation. Concurrent ministry presentations reveal sedimentary uranium deposits with roll-front mineralization suitable for in-situ recovery extraction, positioning Paraguay to evaluate domestic fuel cycle participation alongside technology assessment.